Comparative study of the effects of pyruvate and CG-120 in preventing experimental oxalate urolithiasis in rats.

Title A comparison between effects of pyruvate and herb medicines in preventing experimental oxalate urolithiasis in rats

A comparison between effects of pyruvate and herb medicines in preventing experimental oxalate urolithiasis in rats.

Sodium pyruvate, choreito (a herbal preparation), and urajirogashi (a herb) were added to a calcium-oxalate lithogenic diet (a glycolic-acid diet) to determine their effects in preventing lithogenicity. Male Wistar-strain rats which had been fed the glycolic-acid diet developed marked urinary calculi within 4 weeks. Rats in the groups fed a pyruvate diet had, however, almost no stones in the ur...

Preventive effects of the aqueous extract of Cichorium intybus L. flower on ethylene glycol-induced renal calculi in rats

Objective: Urolithiasis remains a global problem. Despite the availability of numerous methods, no definite therapeutic agent has been yet introduced for the prevention or treatment of kidney stones. In this study, we evaluated the possible preventive effects of aqueous extract of Cichorium intybus L. (chicory) flowers on ethylene glycol-induced renal calculi in rats. Materials and Methods: A t...

Effect of Citrus Medica Linn. in Urolithiasis Induced by Ethylene Glycol Model

The Objective of this study is to study the Effect of Citrus medica in urolithiasis induced by Ethylene Glycol model. A number of 24 Male Wistar albino rats (250-300 g) were divided in to 4 groups namely Group I (Normal control), Group II (Model control), Group III (Standard-treated, cystone – 750 mg/kg) and Group IV (Citrus medica – 250 mg/kg). Except group I, Ethylene glycol (0.75% v/v in dri...

Effects of sodium citrate, potassium citrate, and citric acid in preventing experimental calcium oxalate urolithiasis in rats.

Male Wistar-strain rats which had been fed a glycolic-acid diet developed severe nephrocalcinosis with urinary calculi within 4 weeks. Rats fed the same diet with citrate salts added had, however, either slight or no nephrocalcinosis without any stones in the urinary system. Nephrocalcinosis intermediate between those in the citrate groups and the glycolic-acid group, with some urinary calculi,...